Biomolecular Invariants of Amino Acid Trees

Each of the twenty amino acids are represented by a graph-theoretic tree. Biomolecular descriptors are defined by graphical invariants and are used to determine similarity based on the corresponding Euclidean distances. The results verify that graph-theoretic measures independent of biochemical and biophysical descriptors are valid measures of similarity of amino acids. These results may prove useful for many objectives in proteomics such as protein sequence alignment algorithms and protein folding prediction methods.